Cambridge Healthtech Institute’s 15th Annual
Biophysical Methods
New Strategies and Technologies for Precision Characterization of Complex Biologics
May 11-12, 2027
As biologic pipelines diversify, the need for precise, high-throughput, and predictive characterization tools has never been greater. The Biophysical Methods conference brings together innovators advancing automation, miniaturization, and multi-modal analytics to address the unique challenges of today's complex therapeutic proteins. Topics range from microfluidic assay development and robotic sample handling to in-silico modeling of aggregation, viscosity, and self-association risks. Presentations will spotlight cutting-edge mass spectrometry, imaging, and AI-powered analysis for everything from computationally designed binders to nanobodies and co-formulations. By blending experimental data with modeling frameworks, this program highlights practical solutions for linking biophysical properties to potency, immunogenicity, and clinical performance—helping researchers de-risk development and accelerate promising candidates toward the clinic.
Coverage will include, but is not limited to:
- AI/ML Developability Prediction and Triage
- AI/ML-Assisted Particle and Image Analysis
- Emerging Biophysical Methods
- In silico Prediction of Viscosity and Self-Association
- Lessons Learned from Characterizing Computationally Designed Binders
- New Applications of MS in Early-Stage Characterization
- New Applications of MS in Late-Stage Characterization
- New Technologies for Characterizing Higher-Order Structure
- Physical and Digital Automation in Biophysical Analysis
- Translating Research-Grade Methods into Routine Use
The deadline for priority consideration is October 23, 2026.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation:
- To submit a podium presentation, please click here.
- To become a sponsor, click here.
- To present a poster, click here.
- To sign up to attend, click here.